MLN-4924 hydrochloride , MLN 4924 hydrochloride , MLN4924 hydrochloride
Pevonedistat hydrochloride (MLN4924 hydrochloride) is a selective and potent NEDD8 activating enzyme inhibitor (IC50: 4.7 nM) that induces apoptosis and cell cycle inhibition in cancer cells, and is used in the study of acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). Pelubiprofen has been used in the study of AML and MDS.)
Molecular Weight:
479.98
Purity:
98.44%
CAS Number:
[1160295-21-5]
Formula:
C21H26ClN5O4S
Target:
NEDD8|||Apoptosis
T16117
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