Muramyl dipeptide (MDP) is a synthetic immunoreactive peptide, consisting of N-acetyl muramic acid attached to a short amino acid chain of L-Ala-D-isoGln. It indirectly decreases osteoclast differentiation by reducing the RANKL/OPG ratio and directly increases osteoblast differentiation by up-regulating Runx2 gene expression through MAPK pathways, thereby inducing bone formation via Runx2.
Molecular Weight:
492.48
Purity:
98.00%
CAS Number:
[53678-77-6]
Formula:
C19H32N4O11
Target:
p38 MAPK|||NOD|||NOD-like Receptor (NLR)
T16159
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