NKH477 (Colforsin dapropate hydrochloride) is a derivative of forskolin with antidepressant activity. It inhibits ACh-induced Ca2+ mobilization by acting on ionomycin-sensitive storage sites. NKH477 is an adenylyl cyclase activator with bronchodilatory effects, inhibiting the production of CTL, T-cell proliferation in mixed lymphocyte reactions (MLR), as well as IL-2 production and mitogen responses.
Molecular Weight:
546.09
Purity:
98.00%
CAS Number:
[138605-00-2]
Formula:
C27H44ClNO8
Target:
Adenylate cyclase
T16332
T16332
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