NU6140 is a selective inhibitor of CDK2-cyclin A (IC50, 0.41 µM). It shows 10- to 36-fold selectivity over other CDKs. NU6140 also effectively inhibits Aurora A and Aurora B (IC50s: 67 and 35 nM, respectively). It also enhances the apoptotic effect and has anti-cancer activity.
Molecular Weight:
422.52
Purity:
98.04%
CAS Number:
[444723-13-1]
Formula:
C23H30N6O2
Target:
CDK|||Aurora Kinase
T16359
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