Oglemilast (GRC 3886) suppresses pulmonary cell infiltration, including eosinophilia and neutrophilia in vitro and in vivo. Oglemilast is an effective and orally active phosphodiesterase-4 (PDE4) inhibitor (IC50: 0.5 nM for PDE4D3). Oglemilast has the potential for inflammatory airway diseases.
Molecular Weight:
516.3
Purity:
98.11%
CAS Number:
[778576-62-8]
Formula:
C20H13Cl2F2N3O5S
Target:
PDE
T16379
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