Penciclovir (BRL 39123) is a Herpesvirus Nucleoside Analog DNA Polymerase Inhibitor. In HSV infected cells, penciclovir is phosphorylated by viral thymidine kinase and subsequently converted by cellular kinases into the active metabolite, penciclovir triphosphate, which competitively inhibits viral HSV polymerase by blocking deoxyguanosine triphosphate substrate binding. As a result, herpes viral DNA synthesis and replication are selectively inhibited.
Molecular Weight:
253.26
Purity:
98.84%
CAS Number:
[39809-25-1]
Formula:
C10H15N5O3
Target:
HCV Protease|||HSV|||Antifection
T1643
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