PBIT inhibits JARID1B histone demethylase (IC50 of about 3 µM). PBIT also inhibits JARID1A and JARID1C (IC50s of 6 µM and 4.9 µM, respectively). PBIT is a specific inhibitor of the Jumonji AT-rich Interactive Domain 1 (JARID1) enzymes .
Molecular Weight:
241.31
Purity:
99.61%
CAS Number:
[2514-30-9]
Formula:
C14H11NOS
Target:
Histone Methyltransferase|||Histone Demethylase
T16435
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