Darigabat (PF-06372865) is an orally active and selective GABAA receptor modulator that crosses the blood-brain barrier and exhibits anxiolytic activity, with Ki values of 2.9 nM, 21 nM, and 134 nM for alpha2, alpha1 PAM, and alpha2 PAM, respectively.Darigabat is used in the study of anxiety disorders and epilepsy.
Molecular Weight:
440.49
Purity:
98.42%
CAS Number:
[1614245-70-3]
Formula:
C22H21FN4O3S
Target:
GABA Receptor
T16489
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