L785298 , Fosaprepitant dimeglumine salt , MK-0517
Fosaprepitant dimeglumine (MK-0517) is the dimeglumine salt form of fosaprepitant, a water-soluble, N-phosphorylated prodrug of aprepitant with antiemetic activity. Upon intravenous administration and rapid conversion to aprepitant, this agent selectively binds to human substance P/neurokinin 1 (NK1) receptors in the central nervous system (CNS), inhibiting receptor binding of endogenous substance P and preventing substance P-induced emesis.
Molecular Weight:
1004.83
Purity:
99.03%
CAS Number:
[265121-04-8]
Formula:
C37H56F7N6O16P
Target:
Neurokinin receptor
T1790
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