(S,R,S)-AHPC-C2-PEG4-N3 (VH032-C2-PEG4-N3) is a synthesized E3 ligase ligand-linker conjugate that combines the (S,R,S)-AHPC-based VHL ligand with a 4-unit polyethylene glycol (PEG) linker, used in PROteolysis TAgeting Chimera (PROTAC) technology. This compound aids in the formation of vRucaparib-TP4, a potent PARP1 degrader with a half-maximal degrading concentration (DC50) of 82 nM[1].
Molecular Weight:
703.85
Formula:
C33H49N7O8S
Target:
Others|||E3 Ligase Ligand-Linker Conjugates
T18662
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