XSJ05, a derivative of camptothecin (CPT), exhibits anti-cancer activity by inhibiting topoisomerase I (Topo I). This compound induces DNA double-strand breaks, leading to DNA damage. Furthermore, XSJ05 stifles the growth of colorectal cancer (CRC), halts the cell cycle in the G2/M phase, and induces apoptosis.
Molecular Weight:
539.6
CAS Number:
[1461652-87-8]
Formula:
C29H25N5O4S
Target:
Topoisomerase|||Apoptosis
T200042
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