PMED-1, a beta-catenin inhibitor, effectively suppresses beta-catenin activity in hepatoblastoma cells and various HCC (Hepatocellular Carcinoma) cells with IC50 values ranging from 4.87 to 32 µM. It impedes cell proliferation by disrupting the interaction between beta-catenin and CREB-binding protein, thus affecting Wnt signaling pathways. PMED-1 is utilized in cancer research studies.
Molecular Weight:
335.38
CAS Number:
[491828-75-2]
Formula:
C20H18FN3O
Target:
Wnt/beta-catenin
T200065
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