VEGFR-2/InhA-IN-1, a dual inhibitor based on pyrazole, targets InhA and VEGFR, exhibiting both anti-tuberculosis and anti-angiogenic properties. It demonstrates effective antibacterial activity against the Mycobacterium tuberculosis H37Rv strain (MIC = 6.25 µg/mL) and significantly suppresses VEGFR-2 activity (IC 50 = 15.27 nM).
Molecular Weight:
406.84
Formula:
C22H16ClFN4O
Target:
VEGFR|||Antibacterial
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