WK88-1, an inhibitor of Hsp90, effectively induces the degradation of various oncogenic signaling molecules, including EGFR, ErbB2, and ErbB3, in the gefitinib-resistant H1975 cell line. This leads to subsequent growth arrest and apoptosis.
Molecular Weight:
502.64
CAS Number:
[958888-32-9]
Formula:
C28H42N2O6
Target:
Apoptosis|||HSP
T200115
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