TMU 35435 is an inhibitor of histone deacetylases (HDAC). It enhances radiosensitivity by inducing the accumulation of misfolded proteins and autophagy (autophagy) in TNBC, and inhibits the NHEJ pathway through ubiquitination of the catalytic subunit of DNA-dependent protein kinase (DNA-PKcs).
Molecular Weight:
379.45
CAS Number:
[2231800-32-9]
Formula:
C22H25N3O3
Target:
Autophagy|||HDAC
T200171
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