GBM CSCs-IN-1 (Compound (-)-20), a rocaglate derivative, potently inhibits glioblastoma stem cells (GBM CSCs) and exhibits an EC50 of 45 nM by targeting the RNA helicase DDX3. Additionally, it induces apoptosis in these cells.
Molecular Weight:
633.51
Formula:
C28H29BrN2O8S
Target:
Apoptosis
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