FO-4-15 is an activator of mGluR1/CaMKIIalpha. It exhibits protective effects against H2O2 in human neuroblastoma (SH-SY5Y) cells. In mice with Alzheimers disease, FO-4-15 enhances cognitive function by activating the mGluR1/CaMKIIalpha pathway, reducing Abeta accumulation, Tau hyperphosphorylation, and synaptic damage.
Molecular Weight:
388.44
CAS Number:
[1030759-58-0]
Formula:
C18H20N4O4S
Target:
CaMK
T200203
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