HS-345, a TrkA/Akt inhibitor, exhibits potent anti-pancreatic cancer properties. This compound inhibits the growth and proliferation of pancreatic cancer cells by blocking the TrkA/Akt signaling pathway and induces cell apoptosis (Apoptosis). Additionally, HS-345 inhibits angiogenesis by reducing the expression of HIF-1alpha and VEGF. It holds promise for use in pancreatic cancer research.
Molecular Weight:
394.45
CAS Number:
[1462329-41-4]
Formula:
C19H18N6O2S
Target:
Akt|||Trk receptor
T200230
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