Sabialimon P (compound 16), with an IC50 of 18.12 µM, functions as a NO release inhibitor and exhibits anti-inflammatory properties. It effectively diminishes the secretion of TNF-alpha, iNOS, IL-6, and NF-kappaB, and suppresses the expression of COX-2 and NF-kappaB/p65 in LPS-induced RAW264.7 cells.
Molecular Weight:
486.73
CAS Number:
[2267333-96-8]
Formula:
C31H50O4
Target:
Interleukin|||TNF|||COX|||NF-kappaB|||NO Synthase
T200238
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