INI-4001, a TLR7/8 agonist, exhibits EC50 values of 1.89 µM and 4.86 µM for TLR7 and TLR8, respectively. This compound induces signal transduction and SEAP production through TLR7 and TLR8. Furthermore, INI-4001 stimulates the production of high-affinity, fentanyl-specific antibodies, effectively preventing fentanyl from crossing the human blood-brain barrier. It serves as an effective adjuvant in anti-fentanyl vaccines for individuals with opioid use disorder (OUD).
Molecular Weight:
1141.5
CAS Number:
[2549050-07-7]
Formula:
C59H109N6O13P
Target:
TLR
T200260
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