EGFR/PI3Kalpha-IN-1 (compound 30k), a dual EGFR/PI3Kalpha inhibitor, exhibits potent activity with IC 50 values of 3.6 nM (EGFRL858R/T790M) and 30 nM (PI3Kalpha). It effectively inhibits tumor cell proliferation and demonstrates significant anticancer activity.
Molecular Weight:
916.06
Formula:
C50H49N11O5S
Target:
PI3K|||EGFR
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