CCT070535 inhibits TCF-dependent transcription at the TCF level, displaying GI50 values of 17.6 µM in HT29 (APC mutation), 11.1 µM in HCT116 (oncogenic beta-catenin), 11.8 µM in SW480 (APC mutation), and 13.4 µM in SNU475 (Axin mutation) cells.
Molecular Weight:
398.24
CAS Number:
[485319-41-3]
Formula:
C20H13Cl2N3O2
Target:
Wnt/beta-catenin
T200294
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