JBJ-08-178-01, a mutant-selective tyrosine kinase inhibitor, targets (HER2) human epidermal growth factor receptor 2 and exhibits antitumoral activity. This compound not only diminishes HER2s kinase activity and protein levels through the induction of proteasomal degradation of the receptor but also shows promise in non-small-cell lung cancer research.
Molecular Weight:
562.62
CAS Number:
[2401867-58-9]
Formula:
C31H30N8O3
Target:
Proteasome|||Others
T200308
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