WB436B, a highly selective STAT3 inhibitor, effectively targets and inhibits STAT3-Tyr705 phosphorylation along with the expression of STAT3 target genes. It exhibits cytotoxic effects on pancreatic cancer cells by inducing apoptosis. Furthermore, WB436B suppresses tumor growth and metastasis in pancreatic cancer mouse models, thereby prolonging the survival of tumor-bearing mice.
Molecular Weight:
436.49
CAS Number:
[2248552-84-1]
Formula:
C21H20N6O3S
Target:
Apoptosis|||STAT
T200318
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