GPX4-IN-13 (compound 16), a GPX4 inhibitor, exhibits anticancer properties by diminishing the expression of GPX4, thereby reducing thyroid cell proliferation and inducing ferroptosis. Additionally, this compound effectively inhibits the growth of three distinct thyroid cancer cell lines: N-thy-ori-3-1 (IC 50 =8.39 µM), MDA-T32 (IC 50 =10.28 µM), and MDA-T41 (IC 50 =8.18 µM).
Molecular Weight:
353.37
CAS Number:
[2644044-43-7]
Formula:
C23H15NO3
Target:
Glutathione Peroxidase|||Ferroptosis
T200339
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