(8R)-8-Hydroxyepoxyboetirane A is a neuroactivating compound that interacts with PKCdelta-C1B. This compound binds into the PKC enzyme pocket through hydrogen bonds with glycine-253, leucine-251, and threonine-242. It induces the release of NRG1 and promotes the differentiation of neural stem cells into neurons. (8R)-8-Hydroxyepoxyboetirane A holds potential for research into nervous system disorders.
Target:
PKC
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