mGluR2 modulator5 (Compound 11) is a selective negative allosteric modulator with oral activity, exhibiting an IC50 of 8.9 nM. Pharmacokinetic studies in rats have demonstrated its effective penetration through the blood-brain barrier. This compound is utilized in research related to cognitive and neurological functions in mood disorders, contributing to the field of neurological diseases.
Molecular Weight:
386.37
CAS Number:
[1639898-35-3]
Formula:
C20H17F3N4O
Target:
GluR
T200564
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