Anti-osteoporosis agent-11 (compound 3k) is an anti-osteoporosis compound targeting osteoclasts. It exhibits its most prominent effect by inhibiting osteoclast differentiation, with an IC50 value of 0.36 µM. Additionally, Anti-osteoporosis agent-11 suppresses osteoclast formation, bone resorption, and the expression of osteoclast-specific genes by blocking the RANKL-induced mitogen-activated protein kinase (MAPK) and NF-kappaB signaling pathways.
Molecular Weight:
497.31
CAS Number:
[2869099-50-1]
Formula:
C23H17NO2Se2
Target:
p38 MAPK|||NF-kappaB|||RANKL/RANK
T200650
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