SJYHJ-026 (compound 37) is a pregnane X receptor (PXR) degrader with a DC50 value of 86.6 nM and a maximum degradation efficacy of 66.4%. This compound demonstrates cytotoxicity in SNU-C4 HiBiT-PXR KI cells, with IC50 values of 97.4 µM (24 h) and 99.5 µM (72 h).
Molecular Weight:
1125.42
Formula:
C60H84N8O11S
Target:
PROTACs
T200826
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