A-889425 is a selectively active oral TRPV1 receptor antagonist with IC50 values of 335 nM (rat) and 34 nM (human). This compound effectively penetrates the central nervous system, reducing mechanical allodynia and the response of spinal neurons to mechanical stimuli in rat paws following inflammation induced by Complete Freunds Adjuvant.
Molecular Weight:
425.42
CAS Number:
[1072921-02-8]
Formula:
C19H18F3N3O3S
Target:
TRP/TRPV Channel
T200890
* VAT and and shipping costs not included. Errors and price changes excepted
