ZG-2305 is a selective, orally active inhibitor of FIH with Ki values of 79.6 nM and 2786 nM for FIH and PHD2, respectively. It increases EGLN3 gene expression, reduces cellular triglyceride levels, and decreases lipid accumulation, making it suitable for obesity and fatty liver disease research.
Molecular Weight:
408.19
CAS Number:
[2962103-54-2]
Formula:
C17H11Cl2N3O5
Target:
HIF
T200939
T200939
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