Bfl-1-IN-5 (Compound (R,R,S)-26) is a selective inhibitor of Bfl-1, demonstrating an IC50 of 0.022 µM. This compound enhances the activity of caspase-3/7, with an EC50 of 0.37 µM, and also inhibits the viability of SU-DHL-1 cells, showing an EC50 of 1.3 µM.
Molecular Weight:
443.46
Formula:
C24H24F3N3O2
Target:
Bcl-2 Family|||Caspase
T201041
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