PROTAC c-Met degrader-1, CAS [[3056647-52-7]] Preis auf Anfrage

Product Overview

• Article Name: PROTAC c-Met degrader-1, CAS [[3056647-52-7]] Preis auf Anfrage
• Biozol Catalog Number: TGM-T201057
• Supplier Catalog Number: T201057
• Alternative Catalog Number: TGM-T201057-10MG,TGM-T201057-50MG
• Manufacturer: TargetMol
• Category: Biochemikalien

Product Description

PROTACc-Met degrader-1 (Compound Met-DD4) is an orally effective PROTAC degrader targeting c-Met with a DC50 of 6.21 nM. It inhibits the proliferation of c-Met-addicted MKN-45 cells with an IC50 of 4.37 nM and causes cell cycle arrest in the G0/G1 phase. In a xenograft mouse model using MKN-45 cells, PROTACc-Met degrader-1 demonstrates antitumor activity.

Product Properties

• Molecular Weight: 820.87
• CAS Number: [3056647-52-7]
• Formula: C45H41FN10O5
• Target: PROTACs|||c-Met/HGFR

Images

T201057