Claturafenib (PF-07799933) is a brain-permeable, selective, all-mutant BRAF inhibitor with broad inhibitory effects on pERK levels in HT29 cells.Claturafenib has shown antitumor activity in preclinical studies in both BRAF V600- and non-V600-mutant cancers and can be used in combination with MEK inhibitors.
Molecular Weight:
490.31
Purity:
99.99%
CAS Number:
[2754408-94-9]
Formula:
C18H15Cl2F2N5O3S
Target:
PERK|||Raf
T201081
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