PROTAC ALK degrader-3 (4B) is an orally active PROTAC-based ALK degrader, efficiently inducing sustained degradation of ALK fusion protein and significant inhibition of downstream pathways in Karpas 299 cells with an IC50 of 119.33 nM. This compound exhibits antitumor activity.
Molecular Weight:
966.59
Formula:
C50H60ClN9O7S
Target:
ALK|||PROTACs
T201107
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