SJ46420, a potent and selective precursor variant of SJ46421, functions as a BRD3 PROTAC degrader through a KLHDC2-dependent mechanism. This compound specifically degrades BRD3, which concurrently results in the partial reduction of BRD2 or BRD4 levels.
Molecular Weight:
851.44
Formula:
C43H43ClN8O5S2
Target:
PROTACs|||Epigenetic Reader Domain
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