OES2-0017 exhibits strong synergistic effects and growth inhibition in collaboration with polyamines within a low micromolar range. At low concentrations, OES2-0017 inhibits spermidine/spermine N1-acetyltransferase (SpeG) (IC50: 34.82 µM) and other polyamine detoxifying enzymes, while at higher concentrations, it disrupts bacterial membranes.
Molecular Weight:
242.44
CAS Number:
[5538-95-4]
Formula:
C15H34N2
Target:
Others|||Antibacterial
T201146
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