SMIP34 is an inhibitor of PELP1, binding to this target with a dissociation constant (Kd) of 37.4 µM. It demonstrates efficacy in inhibiting the proliferation of cancer cells and tumor progression. Specifically, SMIP34 is effective in breast cancer research, showing activity against wild-type (WT), mutant (MT) estrogen receptor-positive (ER+), and treatment-resistant (TR)-ER+ breast cancers.
Molecular Weight:
486.01
CAS Number:
[1189710-20-0]
Formula:
C25H32ClN5O3
Target:
Apoptosis
T201153
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