Antifungalagent 122 (compound 201), a potent and broad-spectrum antifungal agent, prevents the phase shift in fungi and the formation of fungal biofilms. This compound effectively inhibits the enzymatic activity of CYP3A4-M and CYP3A4-T, with IC50 values of 2.11 and 4.53 µM, respectively. Notably, Antifungalagent 122 exhibits no cytotoxicity.
Molecular Weight:
508.51
CAS Number:
[3054212-80-2]
Formula:
C28H24F4N4O
Target:
Cytochromes P450|||Antifungal
T201245
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