Ulacamten, also known as CK-4021586 or CK-586, is an orally bioavailable and highly selective cardiac myosin inhibitor that enhances the transition of myosin into a force-generating state without altering calcium handling, demonstrating sub-micromolar biochemical potency and improving left ventricular systolic function in preclinical models while maintaining myocardial energetic efficiency and minimizing off-target activity against skeletal and smooth muscle myosin.
Molecular Weight:
405.44
CAS Number:
[2830607-59-3]
Formula:
C21H25F2N3O3
Target:
Myosin
T201288
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