MED6-189, an analog of kalihinol, disrupts the apicoplast functions and vesicular transport in the malignant malaria parasite (P. falciparum, IC50 < 50 nM). The compound specifically targets the apicoplast, which is a non-photosynthetic plastid essential for isoprenoid synthesis, found in most apicomplexan parasites.
Molecular Weight:
274.4
CAS Number:
[2650073-66-6]
Formula:
C17H26N2O
Target:
Parasite
T201291
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