ZX703 (compound 5I) is a GPX4-targeting PROTAC that induces efficient, dose- and time-dependent degradation of GPX4 through both ubiquitin-proteasome and autophagy-lysosome pathways, ZX703 results in reactive oxygen species accumulation, ferroptosis induction, and strong mechanistic relevance for cancer biology and ferroptosis-focused therapeutic research.
Molecular Weight:
1039.68
Purity:
99.72%
Formula:
C54H67ClN8O9S
Target:
PROTACs|||GPX
T201367
T201367
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