(E)-PHCCC, acting as a positive allosteric modulator (PAM) of the mGluR4, enhances the activity of the receptors endogenous ligand (glutamate). It demonstrates activity in a calcium mobilization assay in CHO cells, with an EC50 of 3.2 µM.
Molecular Weight:
294.31
CAS Number:
[177610-87-6]
Formula:
C17H14N2O3
T201435
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