L134, an effective PROTAC BRD4 degrader, exhibits a DC50 value of 7.36 nM. The degradation of BRD4 by L134 is mediated through the ubiquitin-proteasome system in a DCAF11-dependent manner.
Molecular Weight:
962.47
Formula:
C48H51ClF3N7O7S
Target:
Epigenetic Reader Domain|||PROTACs
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