Octyl Orlistat, CAS [[1243011-56-4]] Preis auf Anfrage

Product Overview

• Article Name: Octyl Orlistat, CAS [[1243011-56-4]] Preis auf Anfrage
• Biozol Catalog Number: TGM-T202399
• Supplier Catalog Number: T202399
• Alternative Catalog Number: TGM-T202399-10MG,TGM-T202399-50MG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: [(2S)-1-[(2S,3S)-3-octyl-4-oxooxetan-2-yl]tridecan-2-yl](2S)-2-formamido-4-methylpentanoate , N-Formyl-L-leucine (1S)-1-[[(2S,3S)-3-octyl-4-oxo-2-oxetanyl]methyl]dodecyl ester , L-Leucine, N-formyl-, (1S)-1-[[(2S,3S)-3-octyl-4-oxo-2-oxetanyl]methyl]dodecyl ester

Product Description

Octyl Orlistat, a potential fatty acid synthase (FASN) inhibitor, has demonstrated significant effectiveness in reducing tumor cell proliferation. By targeting FASN and inducing apoptosis, Orlistat is under investigation as an anti-tumor compound. Compared to Cerulenin and C75, Orlistat shows greater inhibitory potency in cell culture and cell lines. In LN229 cells, treatment with 200 µM Orlistat for 48 hours resulted in a 63.9 8.7% reduction in cell growth, while in LT68 cells, the reduction was 76.3 23.7%. Organotypic slice cultures treated with Orlistat exhibited decreased proliferation after Ki67 staining and an increase in caspase-3 cleavage.

Product Properties

• Molecular Weight: 523.79
• CAS Number: [1243011-56-4]
• Formula: C31H57NO5

Images

T202399