RR-49 is an innovative difluorinated analogue. This compound demonstrates exceptional pH sensitivity, showing the same efficacy for DAMGO in MOR cAMP assays at pH 6.5 as it does at pH 7.4, but with a 19-fold increase in potency (IC50). It holds significant promise as an analgesic for treating inflammatory pain with a lower potential for abuse.
Molecular Weight:
372.45
CAS Number:
[2376328-79-7]
Formula:
C22H26F2N2O
T202488
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