Emavusertib Phosphate, CAS [[2376399-38-9]] Preis auf Anfrage

Product Overview

• Article Name: Emavusertib Phosphate, CAS [[2376399-38-9]] Preis auf Anfrage
• Biozol Catalog Number: TGM-T202829
• Supplier Catalog Number: T202829
• Alternative Catalog Number: TGM-T202829-10MG,TGM-T202829-50MG
• Manufacturer: TargetMol
• Category: Biochemikalien

Product Description

Emavusertib Phosphate (also known as CA-4948) is a potent inhibitor of IRAK4 and FLT3, exhibiting antitumor activity. In ABC DLBCL and AML cell lines, it demonstrates significant cellular efficacy. Furthermore, CA-4948 shows moderate to high selectivity across a panel of 329 kinases and possesses favorable ADME and PK profiles, including good oral bioavailability in mice, rats, and dogs. It achieves over 90% tumor growth inhibition in relevant tumor models and correlates excellently with in vivo PD modulation.

Product Properties

• Molecular Weight: 589.49
• CAS Number: [2376399-38-9]
• Formula: C24H28N7O9P
• Target: MyD88|||NF-kappaB|||Apoptosis|||FLT|||IRAK

Images

T202829