KML-010 is a derivative of spiperone. Compared to spiperone, KML-010 exhibits slightly reduced affinity for 5-HT(2A) receptors, almost no affinity for 5-HT(2C) and 5-HT(1A) receptors, and significantly decreased affinity for dopamine D2 receptors. The modification of the N(1)-phenyl ring in spiperone to a methyl group in KML-010 alters its binding characteristics, potentially offering more selective pharmacological properties for specific receptor targeting.
Molecular Weight:
333.4
CAS Number:
[217635-62-6]
Formula:
C18H24FN3O2
T202891
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