ACT-451840 is capable of eliminating both sensitive and resistant strains of Plasmodium falciparum and has the advantages of oral activity, potency, low toxicity, rapid onset of action in all asexual blood stages of Plasmodium, and a mechanism of action similar to that of artemisinin derivatives. In in vivo experiments, ACT-451840 showed excellent antimalarial effects at a dose of 30 mg/kg, with a parasite reduction rate of 99.80%.
Molecular Weight:
750.97
Purity:
96.07%
CAS Number:
[1984890-99-4]
Formula:
C47H54N6O3
Target:
Parasite
T203012
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