TLR4/NF-kappaB-IN-1 (Compound 7x) is an orally bioavailable inhibitor targeting the TLR4/NF-kappaB signaling pathway, with anti-inflammatory properties and the ability to cross the blood-brain barrier. It can alleviate LPS-induced acute neuroinflammation in mice and downregulate the protein expression of TLR4, P-NF-kappaB, and P-IkappaB-alpha.
Molecular Weight:
374.37
CAS Number:
[3050836-94-4]
Formula:
C20H15FN6O
Target:
NF-kappaB|||TLR|||IkappaB/IKK
T203058
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